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產(chǎn)品名稱:重組人LAMP1
英文名稱:Recombinant Human Lysosome-Associated Membrane Glycoprotein 1
產(chǎn)品貨號(hào):JN1839
產(chǎn)品規(guī)格:10μg|50μg|500μg|1mg
本品由我們的哺乳動(dòng)物細(xì)胞表達(dá)系統(tǒng)制備而成,目的基因編碼的Ala29-Met382在C端含有His標(biāo)簽。
LAMP1質(zhì)量控制:>95%(還原性SDS-PAGE)
LAMP1制劑:凍干品
LAMP1保存:
凍干蛋白置于-20℃以下可長期保存,室溫條件下可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4~7℃保存2~7天,可分裝后置于-20℃保存三個(gè)月。
LAMP1復(fù)溶:
打開試劑管前請(qǐng)先離心。
復(fù)溶濃度推薦大于100 μg/ml。
凍干蛋白請(qǐng)溶于ddH2O。
復(fù)溶后,請(qǐng)根據(jù)用量分裝凍存,避免反復(fù)凍融。
關(guān)于LAMP1:
Lysosome-Associated Membrane Glycoprotein 1 (LAMP1) is a single-pass type I membrane protein belo
nging to the LAMP family. LAMP1 is expressed largely in the endosome-lysosome membranes of cells.It shuttles between lysosomes, endosomes, and the plasma membrane. LAMP1 functions to present carbohydrate ligands to selectins and it has also been implicated in tumor cell me
tastasis. It has been proposed LAMP1 can be used as a therapeutic agent for certain cancers, as well as a marker for lysosomal storage disorders and degranulation on lymphocytes such as CD8+ and NK cells. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mo
nonuclear cells(PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation.
根據(jù)您的關(guān)注的
重組人LAMP1,Recombinant Human Lysosome-Associated Membrane Glycoprotein 1,重組人Lysosome-Associated Membrane Glycoprotein 1,重組Lysosome-Associated Membrane Glycoprotein 1,您可能還對(duì)以下產(chǎn)品有需求:
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關(guān)注
重組人LAMP1,Recombinant Human Lysosome-Associated Membrane Glycoprotein 1,重組人Lysosome-Associated Membrane Glycoprotein 1,重組Lysosome-Associated Membrane Glycoprotein 1的同時(shí),為您推薦更多您可能感興趣的產(chǎn)品:
名稱:重組人白介素36受體α(IL-36Ra)
貨號(hào):JN0347
規(guī)格:10μg|50μg|500μg|1mg
本品由我們的大腸桿菌表達(dá)系統(tǒng)制備,目的基因編碼的Met1-Asp155表達(dá)純化而來。
IL-36Ra/IL-1F5質(zhì)量控制:>95%(還原性SDS-PAGE)。
IL-36Ra/IL-1F5制劑:凍干品
IL-36Ra/IL-1F5保存:
凍干蛋白可在-20℃長期保存,室溫也可穩(wěn)定保存3周。
復(fù)溶蛋白溶液可在4~7℃保存2~7天。
復(fù)溶后建議分裝凍存在-20℃,可保存3個(gè)月,應(yīng)避免反復(fù)凍融。
IL-36Ra/IL-1F5復(fù)溶:
1、試劑開蓋前請(qǐng)先離心。
2、復(fù)溶濃度應(yīng)大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復(fù)溶后根據(jù)使用量分裝保存,避免反復(fù)凍融。
關(guān)于IL-36Ra/IL-1F5:
Human Interleukin-36 Receptor Antago
nist (IL-36RN) is a secreted protein which belo
ngs to the Interleukin 1 cytokine family (IL-1 family). IL-36RN is predominantly expressed in keratinocytes but not in fibroblasts, endothelial cells or melanocytes. IL-36RN is also detected in the spleen, brain leukocyte and macrophage cell types. Increased in lesio
nal psoriasis skin. IL-36RN is a highly and a specific antago
nist of the IL-1 receptor-related protein 2-mediated respo
nse to Interleukin 1 family member 9 (IL1F9). Dysregulated ex
pression of novel ago
nistic and antago
nistic IL-1 family member ligands can promote cutaneous inflammation, revealing potential novel targets for the treatment of inflammatory skin disorders. Human and mouse IL-36RN share 90% sequence identity.
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