抗體 名：Dvl-2 (10B5)抗體

規格：200ug

Santa Cruz是美國也是上zui大的抗體生產廠家，提供抗體種類多達兩萬多種，幾乎覆蓋了目前生命科學研究的各個新領域，其每種抗體又有多個克隆可選擇，并有對應蛋白標準品及相關產品，為免疫學研究工作提供了大的方便。
產品介紹：

Dvl-2 (10B5)抗體基因信息：

Mammalian homologs of the Drosophila dishevelled (Dsh) gene have been identified, including Dvl-1, Dvl-2 and Dvl-3. The mammalian dishevelled proteins contain three homologous domains, two of which are unrelated to any other known protein. The third region is homologous to the discs-large homology domain of Drosophila discs-large-1, a tumor suppressor protein. Like their Drosophila counterpart, the dishevelled proteins are thought to be involved in embryogenesis. Overexpression of Dvl-1 has been shown to inhibit the phosphorylation of tau by GSK-3ß. This finding may prove to be important in Alzheimer’s studies, which have shown that tau is hyperphosphorylated. In Drosophila, Dsh is a component of the frizzled signaling pathway. Both mammalian dishevelled and frizzled proteins are components of the Wnt signalling pathway.