抗體 名：DR3 (H-300)抗體

規(guī)格：200ug

Santa Cruz是美國也是上zui大的抗體生產廠家，提供抗體種類多達兩萬多種，幾乎覆蓋了目前生命科學研究的各個新領域，其每種抗體又有多個克隆可選擇，并有對應蛋白標準品及相關產品，為免疫學研究工作提供了大的方便。
產品介紹：

DR3 (H-300)抗體基因信息：

Tumor necrosis factor (TNF)-related cytokines are pleiotropic factors that initiate various cellular processes including cell death, proliferation and differentiation. Their effects are mediated by a family of receptors which includes TNF-R1, TNF-R2, NGFR (nerve growth factor receptor) and FAS. The members of this family are type I membrane receptors and are charaterized by the presence of cysteine-rich repeats in their extracellular domains. Several of these receptors, including TNF-R1 and FAS, contain a region of intracellular homology, designated the death domain, known to signal apoptosis. A new death domain member of this family, DR3 (also designated Wsl-1, APO-3, TRAMP and LARD) has been shown to induce apoptosis and activation of NF?B. DR3 is most similar in sequence to TNF-R1, but is more restricted in tissue distribution. DR3 is highly expressed in thymocytes and lymphocytes.