Recombinant Human FGF-acidic
產(chǎn)品編號:
100-17A
別名:
Fibroblast Growth Factor-acidic,FGF-1,HBGF-1,ECGF-beta
描述:
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 15.8 kDa protein consisting of 140 amino acid residues.
氨基酸序列:
MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
來源:
E.coli
純度:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
生物活性:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.5 ng/ml in the presence of 10 μg/ml heparin, corresponding to a specific activity of ≥ 2 x 106 units/mg.
交叉反應:
Cow, Mouse, Pig, Rat, Shark, Squid
研究領域:
 |
血管生成/ 心血管 |
 |
癌癥 |
 |
細胞培養(yǎng) |
 |
FGF超家族 |
 |
神經(jīng)生物學 |
 |
增殖 |
 |
干細胞及分化 |
 |
創(chuàng)傷修復 |
原產(chǎn)國:
USA
僅用于研究。不適用于診斷或治療。
免責聲明：以上所展示的[ Recom Human FGF-acidic 100-17A]信息由會員[北京杰輝博高生物技術有限公司]自行提供，內(nèi)容的真實性、準確性和合法性由發(fā)布會員負責。
