產(chǎn)品簡(jiǎn)介
Recombinant Human TGF-2 （mammalian derived）產(chǎn)品編號(hào):100-35B別名:Transforming Growth Factor-2, Glioblastoma-derived T c
公司簡(jiǎn)介
北京杰輝博高生物技術(shù)有限公司依托國(guó)家重點(diǎn)實(shí)驗(yàn)室建立，是由具有資深生命科學(xué)、生物技術(shù)背景及留學(xué)歸國(guó)人員共同創(chuàng)辦的高新技術(shù)企業(yè)。
公司專(zhuān)業(yè)經(jīng)營(yíng)生物科學(xué)領(lǐng)域的實(shí)驗(yàn)儀器、研究試劑和實(shí)驗(yàn)室耗材，致力于向國(guó)內(nèi)外生物科學(xué)研究人員提供一流的服務(wù)。
目前，公司推出的產(chǎn)品涵蓋了生物化學(xué)、分子生物學(xué)、免疫學(xué)、細(xì)胞生物學(xué)等相關(guān)領(lǐng)域，因優(yōu)質(zhì)穩(wěn)定、性?xún)r(jià)比高等特點(diǎn)在廣大科研機(jī)構(gòu)、研究院校及相關(guān)企業(yè)中贏得了良好的聲譽(yù)，從而建立了立體的營(yíng)銷(xiāo)網(wǎng)絡(luò)和擁有廣泛的客戶資源。
公司向廣大用戶提供優(yōu)質(zhì)產(chǎn)品的同時(shí)，始終將客戶服務(wù)和技術(shù)支持放在比產(chǎn)品銷(xiāo)售更重要的位置上，公司聘請(qǐng)了專(zhuān)職、兼職技術(shù)支持人員，為客戶提供專(zhuān)業(yè)性、個(gè)性化的技術(shù)服務(wù)。
公司秉承"先做人，后做事"的理念，堅(jiān)持"以質(zhì)量為生命，以客戶為中心"的宗旨，把最優(yōu)質(zhì)的產(chǎn)品和最貼心的服務(wù)奉獻(xiàn)給廣大客戶。
展開(kāi)
產(chǎn)品說(shuō)明
Recombinant Human TGF-β2 （mammalian derived）
產(chǎn)品編號(hào):
100-35B
別名:
Transforming Growth Factor-β2, Glioblastoma-derived T cell suppressor factor, BSC-1, Cetermin, Polyergin
描述:
The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-β2 has been shown to exert suppressive effects on IL-2 dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno-surveillance of tumor development. Recombinant human TGF-β2 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
氨基酸序列:
ALDAAYCFRN VQDNCCLRPL YIDFKRDLGW KWIHEPKGYN ANFCAGACPY LWSSDTQHSR VLSLYNTINP EASASPCCVS QDLEPLTILY YIGKTPKIEQ LSNMIVKSCK CS
來(lái)源:
HEK293 cells
純度:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
生物活性:
Determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The ED50 was found to be ≤ 0.2 ng/ml, corresponding to a specific activity of ≥ 5 x 106 units/mg.
交叉反應(yīng):
Mouse, Rat
研究領(lǐng)域:
 |
血管生成/ 心血管 |
 |
細(xì)胞凋亡 |
 |
癌癥 |
 |
免疫系統(tǒng) |
 |
炎癥 |
 |
增殖 |
 |
干細(xì)胞及分化 |
 |
TGF超家族 |
 |
創(chuàng)傷修復(fù) |
 |
過(guò)敏 |
原產(chǎn)國(guó):
USA
僅用于研究。不適用于診斷或治療。
| 規(guī)格 |
| A |
1µg |
| B |
5µg |
| |
100µg |
| |
250µg |
| |
500µg |
| |
1mg |
Recombinant Human TGF-β2 100-35B
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