"上海博耀生物銷售BID (7A3) Mouse mAb (Human Specific) #2006，CST原裝品質，價格優惠，訂購BID (7A3) Mouse mAb (Human Speci

"上海博耀生物銷售BID (7A3) Mouse mAb (Human Specific) #2006，CST原裝品質，價格優惠，訂購BID (7A3) Mouse mAb (Human Specific) #2006，詳情請咨詢銷售人員！
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產品名稱：BID (7A3) Mouse mAb (Human Specific) #2006
貨號：2006
品牌：CST(cell signaling)
抗體來源：Mouse
克隆類型： Monoclonal
規格：

No.	Size	Price
2006S	100 ul (10 western blots)	詢價

抗體應用：

Applications	Reactivity	Sensitivity	MW (kDa)	Isotype
W	H	Endogenous	22	Mouse IgG1

Applications Key:  W=Western Blotting
Reactivity Key:  H=Human
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on sequence homology.
特異性/敏感度： BID (7A3) Mouse mAb (Human Specific) detects endogenous levels of full length human BID.
來源及純化方法： Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding the cleavage site of human BID. Antibody is supplied in HEPES buffer with 50% glycerol and less than 0.02% sodium azide.
抗體背景：

Bid is a pro-apoptotic “BH3 domain-only” member of the Bcl-2 family originally discovered to interact with both the anti-apoptotic family member Bcl-2 and the pro-apoptotic protein Bax (1). Bid is normally localized in the cytosolic fraction of cells as an inactive precursor and is cleaved at Asp60 by caspase-8 during Fas signaling, leading to translocation of the carboxyl terminal p15 fragment (tBid) to the mitochondrial outer membrane (2-4). Translocation of Bid is associated with release of cytochrome c from the mitochondria, leading to complex formation with Apaf-1 and caspase-9 and resulting in caspase-9 activation (5-7). Thus, Bid relays an apoptotic signal from the cell surface to the mitochondria triggering caspase activation (8,9).

關鍵詞：CST，抗體，一抗{byao_back}{byao_back2}

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