ApplicationWhen isolating or purifying proteins, benefit from the ul

Application
When isolating or purifying proteins, benefit from the ultimate in convenience to protect your proteins against phosphatase activity. PhosSTOP Phosphatase Inhibitor Cocktail Tablets eliminate the time-consuming search for just the right phosphatase inhibitor.
PhosSTOP is a proprietary blend of phosphatase inhibitors, formulated as a ready-to-use, quick-dissolving, water-soluble tablet. The inhibitor tablets can be used in buffers containing formalin (for formalin fixation).
Achieve immediate, more effective, and convenient inhibition of a broad spectrum of phosphatases across a wide range of sample materials (e.g., mammalian, plant, yeast, and bacteria) with non-toxic PhosSTOP Phosphatase Inhibitor Cocktail Tablets. They are well suited for the purification and detection of phoshorylated proteins.
PhosSTOP Tablets can also be used in combination with the cOmplete Protease Inhibitor Cocktail Tablets to simultaneously protect proteins against dephosphorylation and proteolytic degradation; both inhibitor tablets maintain their activity when used together.
Product Description
Starting concentration: 1 tablet contains phosphatase inhibitors sufficient for 10 ml cell extract or buffer.
Specificity
Protects proteins against dephosphorylation. Inhibits phosphatase classes such as acid and alkaline phosphatases, as well as serine/threonine (PP1, PP2A, and PP2B) and tyrosine protein phosphatases (PTP) in bacterial, mammalian, yeast, and plant extracts.
Solubility/Stability
Soluble in aqueous buffers, or can be added directly to extraction media. The inhibitors are active in buffers containing formalin. Dissolve one tablet per 10 ml aqueous buffer. Alternatively, prepare a 10x stock solution in 1 ml water or 100 mM phosphate buffer, pH 7.0. Higher concentrations of stock solution are possible.
10x Stock solution is stable for 1 month at +2 to +8°C or at least 6 months at -15 to -25°C.
Benefits
Complete protection: Instantly protect your proteins against a broad range of phosphatases. Inhibits acid and alkaline phosphatases, as well as serine/threonine (PP1, PP2A, and PP2B) and tyrosine protein phosphatases (PTP).
Safe: Dissolve the non-toxic PhosSTOP Tablets in aqueous solutions and avoid organic solvents (e.g., DMSO).
Flexible: Use PhosSTOP Tablets in extracts from almost any tissue or cell, including animals, bacteria, plant, or yeast cells.
Suitable for formalin fixation: Maintain phosphorylation status of proteins in histological sections; PhosSTOP phosphatase inhibitors are active in buffers containing formalin (for formalin fixation).
Convenient: Eliminate the time-consuming search for just the right phosphatase inhibitor.
Easy to use: Simply drop a quick-dissolving tablet into your buffer.
Compatible with cOmplete Protease Inhibitor Cocktail Tablets: Obtain cOmplete phosphatase inhibitor and protease inhibitor activity when used in combination with cOmplete Tablets.

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