我公司致力于為客戶提供高純度、低成本的活性重組蛋白，包括重組人葉酸受體α(FOLR1)在內的各類受體、細胞因子、生長因子、轉錄因子、激素、酶、毒性蛋白、病毒抗原等。...

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產品名稱：重組人葉酸受體α(FOLR1)
英文名稱：Recombinant Human Folate Receptor alpha
產品貨號：JN1330
產品規格：10μg|50μg|500μg|1mg

本品由我們的哺乳動物細胞表達系統制備而成，目的基因編碼的Arg25-Ser234在C端含有His標簽。

FOLR1質量控制：＞95%(還原性SDS-PAGE)

FOLR1制劑：凍干品

FOLR1保存：
凍干蛋白置于-20℃以下可長期保存，室溫條件下可穩定保存3周。
復溶蛋白溶液可在4～7℃保存2～7天，可分裝后置于-20℃保存三個月。

FOLR1復溶：
打開試劑管前請先離心。
復溶濃度推薦大于100 μg/ml。
凍干蛋白請溶于ddH2O。
復溶后，請根據用量分裝凍存，避免反復凍融。

關于FOLR1：
Folate receptor alpha(FOLR) belongs to the folate receptor family, and is primarily expressed in tissues of epithelial origin. It is also expressed in kidney, lung and cerebellum. The secreted form is derived from the membrane-bound form either by cleavage of the GPI anchor, or/and by proteolysis catalyzed by a metalloprotease. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. It has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. It is required for normal embryonic development and normal cell proliferation.

根據您的關注的重組人葉酸受體α(FOLR1)，重組Folate Receptor alpha，重組人葉酸受體α，重組葉酸受體α，重組FOLR1，重組人Folate Receptor alpha，Recombinant Human Folate Receptor alpha，rFOLR1，重組人FOLR1，rhFOLR1，您可能還對以下產品有需求：


JN0221 重組人β-NGF(神經生長因子) 10μg|50μg|500μg|1mg
JN0247 重組人FGF2(堿性成纖維細胞生長因子2) 10μg|50μg|500μg|1mg
JN0352 重組人白介素IL-36α(白細胞介素36α) 10μg|50μg|500μg|1mg
JN0751 重組人ADH7(乙醇脫氫酶4μ) 10μg|50μg|500μg|1mg
JN0909 重組人高遷移率族蛋白1(HMGB1) 10μg|50μg|500μg|1mg
JN1031 重組人STAT6(信號轉導子和轉錄激活子6) 10μg|50μg|500μg|1mg
JN1072 重組人NHP2(核仁蛋白家族A成員2) 10μg|50μg|500μg|1mg

關注重組人葉酸受體α(FOLR1)，重組Folate Receptor alpha，重組人葉酸受體α，重組葉酸受體α，重組FOLR1，重組人Folate Receptor alpha，Recombinant Human Folate Receptor alpha，rFOLR1，重組人FOLR1，rhFOLR1的同時，為您推薦更多您可能感興趣的產品：



名稱：重組人MANF(含His標簽)
貨號：JN0208
規格：10μg|50μg|500μg|1mg
本品由我們的哺乳動物表達系統制備，目的基因編碼的Leu25-Leu182在C端含有His標簽。

MANF質量控制：＞95%(還原性SDS-PAGE)。

MANF制劑：凍干品

MANF保存：
凍干蛋白可在-20℃長期保存，室溫也可穩定保存3周。
復溶蛋白溶液可在4～7℃保存2～7天。
復溶后建議分裝凍存在-20℃，可保存3個月，應避免反復凍融。

MANF復溶：
1、試劑開蓋前請先離心。
2、復溶濃度應大于100 μg/ml.
3、凍干蛋白溶于ddH2O中
4、復溶后根據使用量分裝保存，避免反復凍融。

關于MANF：
Mesencephalic astrocyte-derived neurotrophic factor(MANF) is a secreted protein which belongs to the ARMET family. MANF selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. It modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. MANF enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons. MANF inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death. The N-terminal region of ARMET may be responsible for neurotrophic activity while the C-terminal region may play a role in the ER stress response. MANF reduces endoplasmic reticulum (ER) stress and has neurotrophic effects on dopaminergic neurons. Intracortical delivery of recombinant MANF protein protects tissue from ischemic brain injury. MANF has been described as a survival factor for dopaminergic neurons. MANF and a homologous protein, the conserved dopamine neurotrophic factor (CDNF), form a novel evolutionary conserved family of neurotrophic factors. MANF expression was widespread in the nervous system and non-neuronal tissues.

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